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Ionizing radiation of the exposome, multi-exposures, cancers risks and of other diseases in the Constances cohort (CORALE)

The first objective of the CORALE project is to carry out the broadest possible reconstruction of doses of IR from environmental sources (radon, terrestrial and cosmic radiation, food, nuclear installations and other artificial soures), medical (diagnostic and therapeutic procedures) and occupational (nuclear workers but also other industries using radioactive sources, health professionals...) received by participants in the Constances cohort since birth, following the logic of the exposome concept (for its radiological component). The second objective will be to estimate the risks of cancers and other chronic diseases potentially asociated with the cumulative doses received (from several sources of IR and over time) taking into account the potential influence of the context of multi-exposures to other risk factors.